{"id":1900,"date":"2026-10-05T10:59:40","date_gmt":"2026-10-05T10:59:40","guid":{"rendered":"https:\/\/redzine.co.uk\/index.php\/2026\/10\/05\/eat-well-to-age-better-at-a-biological-level-new-research\/"},"modified":"2026-10-05T10:59:40","modified_gmt":"2026-10-05T10:59:40","slug":"eat-well-to-age-better-at-a-biological-level-new-research","status":"publish","type":"post","link":"https:\/\/redzine.co.uk\/index.php\/2026\/10\/05\/eat-well-to-age-better-at-a-biological-level-new-research\/","title":{"rendered":"Eat well to age better at a biological level \u2013 new research"},"content":{"rendered":"<figure><img decoding=\"async\" src=\"https:\/\/images.theconversation.com\/files\/762770\/original\/file-20260929-50-nfg9yt.jpg?ixlib=rb-4.1.1&amp;rect=0%2C0%2C6000%2C4000&amp;q=45&amp;auto=format&amp;w=1050&amp;h=700&amp;fit=crop\" \/><figcaption><span class=\"caption\">Following a good-quality diet for many years can have measurable impacts on ageing.<\/span> <span class=\"attribution\"><a class=\"source\" href=\"https:\/\/www.shutterstock.com\/image-photo\/elderly-enjoying-healthy-outdoor-meal-2849979087?trackingId=c268bb4e-d128-4ff1-a7ae-37448cfcc4f6&amp;listId=searchResults\">Rawpixel.com\/ Shutterstock<\/a><\/span><\/figcaption><\/figure>\n<p>When it comes to healthy ageing, the <a href=\"https:\/\/doi.org\/10.1038\/s41591-025-03570-5\">overall quality of a person\u2019s diet<\/a> matters more than eating any one \u201csuperfood\u201d or nutrient. From the Mediterranean diet to the Nordic diet, specific <a href=\"https:\/\/doi.org\/10.1111\/joim.13728\">eating patterns<\/a> have been shown to reduce the risk of heart disease, physical frailty and cognitive decline. <\/p>\n<p>But while we know <a href=\"https:\/\/theconversation.com\/topics\/diet-261\">diet<\/a> affects our health, we haven\u2019t really been clear until now on the changes it causes inside the body which lead to these benefits. <\/p>\n<p>This is exactly what our <a href=\"https:\/\/doi.org\/10.1186\/s12916-026-05202-2\">latest study<\/a> set out to explore. We found that older adults who ate high-quality diets exhibited biological signs of healthier ageing that could be detected in their blood. These findings offer a clearer picture of the connection between healthy eating and healthy ageing.<\/p>\n<p>We looked at data from 1,769 adults aged 60 and older living in Stockholm, Sweden. Participants completed detailed questionnaires about what they typically ate over the previous year. <\/p>\n<p>Rather than focusing on single nutrients, diet quality was measured using three well-established eating patterns.<\/p>\n<p>The first eating pattern was based on <a href=\"https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.108.816736\">Mediterranean-style eating<\/a>, which involves consuming foods typical of Mediterranean countries \u2013 such as plant foods, wholegrains and fish. The second eating pattern was based on <a href=\"https:\/\/doi.org\/10.3945\/jn.111.157222\">guidelines for reducing chronic disease risk<\/a>, which also place an emphasis on fruits, vegetables, nuts, legumes and avoiding processed and red meats, sugary drinks and trans fats (such as fried foods). <\/p>\n<p>The third eating pattern considered <a href=\"https:\/\/doi.org\/10.3945\/jn.115.228718\">how inflammatory a person\u2019s overall diet was<\/a>. Diet can play an important role in the development of chronic diseases through inflammation. Diets high in processed foods, red meats and sugary drinks have been <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10302286\/\">linked to greater inflammation<\/a>.<\/p>\n<p>Participants received a score for how closely they adhered to each eating pattern. Those who regularly ate foods such as fruits, vegetables, wholegrains, legumes, nuts and fish received higher scores. Those who consumed less favourable components, such as refined grains, sugar-sweetened drinks and red and processed meats, received a lower score. <\/p>\n<p>We then looked at how closely following each pattern related to 54 blood biomarkers related to ageing. Biomarkers are measurable signals of the biological processes unfolding in our bodies every day. The biomarkers we analysed covered metabolism, inflammation, vascular health and brain health. Other factors that could affect the results, such as age, sex, socioeconomic status, physical activity levels and smoking were also accounted for.<\/p>\n<p>Our overall finding was consistent: people following healthier eating patterns had more favourable blood biomarker profiles. Two biomarkers stood out, both linked with all three measures of diet quality.<\/p>\n<p>The first was folate, a B vitamin the body cannot make so it must be obtained from food or supplements. The body needs folate to <a href=\"https:\/\/doi.org\/10.29219\/fnr.v67.10258\">support basic functions<\/a>, including the formation of healthy red blood cells, production of DNA (genetic material) and cell renewal.<\/p>\n<p>People following healthier diets had higher folate levels in their blood. This makes sense, given the healthy eating patterns we looked at generally include foods which are good sources of folate \u2013 such as leafy dark green vegetables, fruits and legumes. <\/p>\n<figure class=\"align-center \">\n            <img decoding=\"async\" alt=\"An assortment of foods that are rich in folate, including avocados, cucumbers, celery and lettuce.\" src=\"https:\/\/images.theconversation.com\/files\/762776\/original\/file-20260929-50-j2fn48.jpg?ixlib=rb-4.1.1&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip\"><figcaption>\n              <span class=\"caption\">Folate plays an important role in healthy ageing.<\/span><br \/>\n              <span class=\"attribution\"><a class=\"source\" href=\"https:\/\/www.shutterstock.com\/image-photo\/products-containing-folic-acid-b9-vitamin-597151175?trackingId=e128ffe3-8509-4635-b29f-c84e297d21c9&amp;listId=searchResults\">Komarina\/ Shutterstock<\/a><\/span><br \/>\n            <\/figcaption><\/figure>\n<p>Maintaining adequate folate levels may be particularly relevant in later life because the body\u2019s ability to absorb and use certain nutrients <a href=\"https:\/\/doi.org\/10.1093\/ajcn\/72.2.529S\">can change with age<\/a>. Low folate levels have also been linked to <a href=\"https:\/\/doi.org\/10.1093\/nutrit\/nuab057\">cognitive decline<\/a>, making sufficient intake through diet especially important with increasing age.<\/p>\n<p>The second biomarker was growth differentiation factor-15 \u2013 a protein that stressed or damaged cells release due to <a href=\"https:\/\/doi.org\/10.1016\/j.biopha.2024.116475\">tissue injury, inflammation or cell death<\/a>. Its levels tend to rise <a href=\"https:\/\/doi.org\/10.1111\/acel.12799\">with age<\/a> and <a href=\"https:\/\/doi.org\/10.1038\/s41591-025-04038-2\">with chronic health conditions<\/a>. <\/p>\n<p>Growth differentiation factor-15 reflects how much internal stress the body is under. Its consistently lower levels in participants who followed healthier diets suggests eating well helps reduce that underlying burden \u2013 regardless of the diet\u2019s exact composition.<\/p>\n<p>Of these three diet quality measures, the one that measured how inflammatory a person\u2019s diet was was linked to the widest range of favourable blood biomarkers \u2013 six in total. These biomarkers were connected to several aspects of health, including blood sugar regulation, appetite and liver, bone and immune function.<\/p>\n<p>The range of biological functions represented by these biomarkers suggests inflammation may be one important pathway <a href=\"https:\/\/doi.org\/10.1016\/j.cytogfr.2024.08.004\">connecting diet with the ageing process<\/a>. Following diets with lower inflammatory potential (such as the <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41211687\/\">Mediterranean-style diet<\/a>) may therefore help support several of the biological systems, many of which play a direct role in how the body ages. <\/p>\n<p>This fits well with <a href=\"https:\/\/doi.org\/10.1038\/s43587-025-00929-8\">our previous research<\/a> which found that people following a less inflammatory diet tended to accumulate chronic diseases more slowly.<\/p>\n<h2>Diet quality<\/h2>\n<p>There were a few caveats with our research. Because diet and blood markers were measured at the same point in time, it\u2019s not possible to establish cause and effect. Diet was self-reported, which can introduce a level of uncertainty. Participants were also relatively healthy and well-educated, and lived in one urban area of Sweden. These characteristics may limit how broadly the findings can be applied to all populations.<\/p>\n<p>Still, our findings add to a <a href=\"https:\/\/doi.org\/10.1038\/s41591-025-03570-5\">broad body of evidence<\/a> linking <a href=\"https:\/\/doi.org\/10.1111\/joim.13728\">healthy eating<\/a> to lower risk of chronic disease, better physical and cognitive function and improved mental wellbeing in older adults. Our research also offers a biological explanation for how, by pointing to the measurable processes happening inside the body that may actually be responsible.<\/p>\n<p>No single food or rigid diet stands out. What matters is the overall quality of the diet, maintained consistently over time. It\u2019s that quality, our study suggests, which may tell part of the story of how well the body ages.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/counter.theconversation.com\/content\/292525\/count.gif\" alt=\"The Conversation\" width=\"1\" height=\"1\" \/><\/p>\n<p class=\"fine-print\"><em><span>Adri\u00e1n Carballo Casla receives funding from the Foundation for Geriatric Diseases at Karolinska Institutet (project numbers 2024:0011 and 2025:0013); the Karolinska Institutet Research Foundation Grants (project number 2024:0017); the David and Astrid Hagel\u00e9n foundation (project number 2024:0005); and the Swedish Research Council for Health, Working Life and Welfare (project number STY-2024\/0005). <\/span><\/em><\/p>\n<p class=\"fine-print\"><em><span>Rachel Ann Da Costa does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.<\/span><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Following a good-quality diet for many years can have measurable impacts on ageing. Rawpixel.com\/ Shutterstock When it comes to healthy ageing, the overall quality of a person\u2019s diet matters more than eating any one \u201csuperfood\u201d or nutrient. From the Mediterranean diet to the Nordic diet, specific eating patterns have been shown to reduce the risk [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1900","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/posts\/1900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/comments?post=1900"}],"version-history":[{"count":0,"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/posts\/1900\/revisions"}],"wp:attachment":[{"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/media?parent=1900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/categories?post=1900"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/redzine.co.uk\/index.php\/wp-json\/wp\/v2\/tags?post=1900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}